SS-B/La antibodies are found primarily in patients suffering from Sjögren’s syndrome (up to 70% in primary Sjögren’s syndrome, up to 50% in secondary Sjögren’s syndrome). For systemic lupus erythematosus, SS-B antibodies are detectable in up to 25% of patients and provide some indications of the prognosis of the disease. Mostly, they are found together with SS-A antibodies; if these autoantibodies are absent, they only appear infrequently.
Testing for SS-B antibodies is indicated for patients with signs and symptoms of a connective tissue disease and in whom the test for antinuclear antibodies (ANA) is positive, especially when symptoms are consistent with Sjögren’s syndrome or lupus erythematosus. In addition to it, in asymptomatic people suspected of having Sjögren’s syndrome, SS-B antibodies can clarify the full picture of the disease.
Tests offered by ORGENTEC Diagnostika
Anti-Nuclear Antibodies HEp-2 (ANA-HEp-2) (ORG 870)