ORGENTEC Autoimmunity Blog

Covering Autoimmune Diseases

Tag: rheumatoid factor

Rheumatoid Arthritis: Is the Incidence of this Autoimmune Disease Rising?

Is the Incidence of Rheumatoid Arthritis Rising?

Is rheumatoid arthritis (RA) actually on the rise? Researchers from the Mayo Clinic in Minnesota say “yes”, and they presented data from a study, published in the June issue of the Arthritis & Rheumatism magazine – even though the authors themselves can only speculate about the reasons why.

Rheumatoid arthritis is on the rise, they found – is increased use of some lower dose birth control pills a factor?

Rheumatoid arthritis is on the rise, they found – is increased use of some lower dose birth control pills a factor?

In that recently published Rheumatoid Arthritis Clinical Study Elena Myasoedova, Cynthia S. Crowson, Hilal Maradit Kremers, Terry M. Therneau, and Sherine E. Gabriel from the Mayo Clinic College of Medicine, Rochester, Minnesota, expanded a previous research from 1955 to 1994, looking at the years 1995 to 2007. To augment the pre-existing study they now focused on the medical records of more than 1,700 residents of Olmstedt County, Minnesota, aged 18 years or older, who had received at least one diagnosis of rheumatoid arthritis (RA).

Yes, RA is on the rise! 

What did they find out? – From 1955 to 1994, the incidence of rheumatoid arthritis had continually been on the decline. That apparently changed beginning in the mid-1990s. When the researchers analyzed patient data from early 1995 to the start of 2005, they found that both the incidence and the prevalence of the condition were rising. (more…)

Rheumatoid Arthritis (RA): Smoking and Rheumatism

There is a Connection between Rheumatoid Arthritis (RA) and Smoking – what are the Reasons?

Smoking might be a trigger for rheumatoid arthritis.

That smoking is unhealthy really isn’t a secret any more. However, it may be less well known that smoking is especially damaging to patients with rheumatoid arthritis (RA) or people with a genetic predisposition towards this autoimmune disease.

Until a few years ago, a coherent explanation of how smoking triggers the break in immunotolerance and why tobacco smoke promotes the onset of autoimmune disease was still missing. A group of Swedish researchers has found one of the missing links in the pathogenic chain between tobacco smoke and rheumatoid arthritis (Makrygiannakis et al., 2008). The scientists from the Karolinska Institute in Stockholm showed that cigarette smoke is directly involved in the development of rheumatoid arthritis. (more…)

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