SS-A/Ro antibodies occur regularly in patients with several different connective tissue diseases including Sjögren’s syndrome (up to 90% of cases), lupus erythematosus (up to 60% of cases), and rheumatoid arthritis. They are also associated with childhood lupus erythematosus, neonatal lupus, and with congenital heart block in infants born to mothers with lupus erythematosus.
Testing for these autoantibodies is indicated for patients with signs and symptoms of a connective tissue disease and in whom the test for antinuclear antibodies (ANA) is positive, especially when symptoms are consistent with Sjögren’s syndrome or lupus erythematosus.
Tests offered by ORGENTEC Diagnostika
Anti-Nuclear Antibodies HEp-2 (ANA-HEp-2) (ORG 870)