Liver Disease Diagnostics: Antibody-Based Diagnosis of Autoimmune Liver Disease
For the launch of our Liver-9-Line immunoblot test (to our press release “Liver Disease Diagnostics by Immunoblot” of May 16, 2011), I dug through a pile of literature on the topic of autoantibody-based diagnosis of autoimmune diseases of the liver. In the last week I picked it all up again and worked through it systematically.
The interior surface of the liver. A reproduction of a lithograph plate from Gray’s Anatomy.
The reason for my renewed interest is that we brought four more ELISA tests for liver diagnostics to the market two weeks ago. They are the Anti-LKM-1, Anti-SLA, Anti-gp210, and Anti-Sp100 tests, all designed for fully automated autoimmune diagnosis with our Alegria system. All four test systems assist the formulation of a diagnosis when autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC) are suspected, or for differential diagnosis when another disorder of the liver is assumed. (more…)
Mobile Health Applications and Their Significance for Medical Education and Healthcare
As we here at ORGENTEC Diagnostika set about developing a smartphone application for our company in mid-September of this year, we had no idea what an exciting field we were entering.
We were also amazed when we began to intensively explore the iTunes App store and Android Market to see “what the others were up to”. We tried out many things, looked at a large variety of very different apps, and loaded our iPhones up with a broad range of apps.
The ORGENTEC Autoimmunity Guide: Three screenshots of our company’s mobile medical app on autoimmunity, autoimmune disorders, and autoimmune diseases diagnostics. – © ORGENTEC Diagnostika, Mainz
We also researched a lot of technical details, reading this blog and that. We learned a great deal about the market shares of the individual mobile operating systems (“Who is winning the race for domination on the mobile operating system market in which corner of the world? Apple’s iOS or the Android OS? Blackberry’s RIM or Windows Phone 7?”). We thus also had to involve ourselves to some extent in some “religious wars” (“iPhone or Android device?” – … there’s no question, is there?). (more…)
Anti-CCP hs (high sensitive)®: a new biomarker for the serological diagnosis of early rheumatoid arthritis
Timely diagnosis is of critical importance to the progression of rheumatoid arthritis (RA) because the rapid implementation of intensive treatment can inhibit damage to the joints and maintain function. In conjunction with medical history, clinical examination, and imaging procedures, serological tests form the foundation for an early diagnosis.
In addition to rheumatoid factors, autoantibodies against citrullinated antigens (ACPA) have proven to be valuable tools for the serological diagnosis of early RA. They have become a critical component of the new 2010 ACR criteria for the classification of RA, and account for three of the six points required to verify a diagnosis of RA. (more…)
Our Point-of-Care-Test rheumachec for Diagnosing Rheumatoid Arthritis – a Highly Accessed Research Article in Arthritis Research & Therapy!
Several days ago, a colleague pointed out to me a publication in the journal Arthritis Research & Therapy that came about largely through collaboration with scientists at ORGENTEC Diagnostika. Needless to say that this article was already familiar to me – already before its initial online publication in the summer of this year, I had read excerpts from it and extensively discussed the work and the results of this evaluation study with co-workers and clients. (more…)
It’s Great When There’s Something to Celebrate!
Last week we had such an occasion at ORGENTEC Diagnostika. The February issue of the Annals of the Rheumatic Diseases, the EULAR Journal, included the results of a clinical evaluation study of our Anti-PR3 hs ELISA. The results are very gratifying for us and reflected well on our product.
The subject of the article? – The effectiveness of our test for the diagnosis of ANCA-associated vasculitis, abbreviated as AAV. This term encompasses autoimmune diseases characterized by the presence of antineutrophil cytoplasmic antibodies, known as ANCA. These diseases include Wegener’s granulomatosis (WG), microscopic polyangiitis (MPA), and Churg-Strauss syndrome (CSS). (more…)
What You Can Learn from this Blog
ORGENTEC’s Autoimmunity Blog is a weblog on autoimmunity, autoimmune diseases, and autoimmune diagnostics. Launched today it will keep you postet with the news & facts on research on autoimmunity as well as therapy and diagnosis of single autoimmune diseases, such as rheumatoid arthritis, lupus, fibromyalgia, celiac disease, and antiphospholipid syndrome.
I look forward to your comments and suggestions!