Juvenile idiopathic arthritis (JIA): How do genes contribute to onset of this autoimmune disease? What about the environment?
Both the genetic groundwork of juvenile idiopathic arthritis (JIA) and the influence of the environment on onset of the disease have thus far seen little research. One of the reasons for this is surely that JIA is a rare disease: only one in a thousand children suffer from juvenile idiopathic arthritis. With such a small number of patients, it is naturally difficult to carry out meaningful studies.
Insights and hypotheses about the epidemiology and pathomechanism of other autoimmune diseases have only in recent years begun to be carried over to JIA and confirmed for this autoimmune disorder. (more…)